Metabolic health is foundational for overall wellness. When your metabolism functions efficiently, you enjoy balanced energy, better weight management, and healthier aging. However, issues like fat storage and blood sugar fluctuations can disrupt this balance.

That’s why doTERRA developed the MetaPWR® System. It’s a holistic solution designed to optimize your metabolic health.*

Backed by clinical research, this system includes several powerhouse products, among them MetaPWR Metabolic Blend and MetaPWR Assist, which work together to promote a healthier, more vibrant you.*

Metabolic Health Is More than Just Energy

To understand the results from clinical research, it’s important to understand that metabolic health isn’t just about how fast you burn calories. It’s also about how efficiently your body converts glucose into energy and stores fat.

Blood sugar levels play a significant role here. When you consume carbs, they break down into glucose, which your cells use for energy.

Let’s examine how both the MetaPWR Blend and MetaPWR Assist help in these areas.

Modulating Fat Cell Behavior in MetaPWR Metabolic Blend

MetaPWR Blend is a proprietary combination of Cinnamon Bark, Peppermint, Lemon, Grapefruit, and Ginger. These essential oils come together to support healthy fat metabolism when ingested.*

doTERRA previously had a blend with these same essential oils called Slim & Sassy^®, but the essential oils were combined in different amounts (or ratios). We wanted to optimize these ratios for even better metabolic performance.

MetaPWR Blend Preclinical Study

To find the best ratio, we first needed mature fat cells. So, we took human adipocytes (adipose fat cells) and used a Differentiation Media (DM) to put them through a maturation process.

After 14 days, the fat cells had matured and accumulated fat droplets, as shown in these images.

On the left are immature cells that are mostly flat and empty of fat. On the right are cells full of fat droplets, which are much larger.

Once we had mature fat cells, we used them to conduct a dose response study with different variations of the essential oil blend.

Slim & Sassy

First, we tested the original blend: Slim & Sassy.

Each image displays the effect the blend had on the mature fat cells in different doses. As you can see, the more Slim & Sassy we included, the less fat accumulated inside the cells, which was exciting!

But it was something we already knew, and we wanted to see if we could inhibit fat deposition even further.

Trial Blend 2

Unfortunately, our second formulation didn’t perform as well as Slim & Sassy when it came to inhibiting fat deposition. It still had an effect, but the results weren’t near what we wanted. But they did prove how important the ratios of essential oils are when creating a blend.

MetaPWR Metabolic Blend

These last results display the formulation of what would be called MetaPWR Blend.

As you can see, it outperformed both blends immensely, which was extremely exciting news! We had the official new metabolic blend.*

This graph displays how the three blends worked differently from each other.

Key:

Y = Steatosis (fat buildup)

X = Micrograms of essential oil per mL of growth solution

These results suggest by incorporating MetaPWR Metabolic Blend into your daily routine, you can help target and reduce adipose fat cells when it’s ingested, thereby supporting a healthier, more efficient metabolism.*

MetaPWR Assist: Blood Sugar Regulation with Mulberry Leaf Extract

While MetaPWR Metabolic Blend focuses on fat storage, MetaPWR Assist targets another critical aspect of metabolism: blood sugar stabilization.

Simple Versus Complex Carbohydrates

Remember, when you consume carbs, they break down into glucose, which your cells use for energy.

However, not all carbs are created equal.

• Simple carbohydrates (sugary snacks, white bread, and more) are more rapidly metabolized, often followed by energy crashes.
• Complex carbohydrates (fibrous fruits and veggies, whole grains, and more) provide a steadier release of glucose, supporting more balanced energy.

You may have already noticed these fluctuations affect your energy levels, but did you know they affect your long-term health? That’s the problem we wanted to address with MetaPWR Assist.

Mulberry Leaf Extract

One of the most prominent and important ingredients in MetaPWR Assist is mulberry leaf extract. It helps all carbohydrates—fast and slow—act like slow ones.*

The iminosugars of the mulberry leaves interact with the digestive enzymes that metabolize carbohydrates, slowing their digestion so the glucose doesn’t hit your bloodstream as quickly.

Why Does This Matter?

Frequent glucose spikes stress your body, which triggers the inflammatory system, leading to energy crashes and increased fat storage. Over time, this cycle can contribute to metabolic dysfunction and signs of premature aging.

Think of your body like a car. If you put your foot to the floor to accelerate and then slam on the brakes, it’s going to wear down your car much more quickly.

By helping to smooth out those spikes with a healthy diet enriched with complex carbohydrates and MetaPWR Assist, you can support better balanced energy and reduce the likelihood of harmful effects like oxidative stress and quicker biological aging. It also helps with your energy levels!*

MetaPWR Assist Clinical Trial

To test the effectiveness of MetaPWR Assist, we conducted a double-blind, placebo-controlled trial for two weeks. The trial included 15 participants, all of whom had a standardized meal at breakfast and continuous glucose monitoring throughout the day. None of the participants had diabetes. They took a placebo for the first week of the trial and MetaPWR Assist for the second week.

Their blood glucose levels were measured every 15 minutes, day and night, giving us fantastically insightful data.

Overall, the trial showed that when participants took MetaPWR Assist, they had fewer glucose spikes and more sustained glucose levels throughout the day.

Here’s an example of what the data looked like for one of the trial participants. On the first Saturday of the trial, this participant was still using the placebo. The curve led to an average continuous blood glucose measurement of 102.

The next Saturday, the participant took the real MetaPWR Assist. The participant’s glucose measurement dropped 13% in just one week! Also, the peaks and valleys in the measurements were smoother and gentler, which is exactly what you’d want in this product. You can see a reduction in the large glucose spike when the participant took MetaPWR Assist before the standardized high carbohydrate meal.*

Synergy Between MetaPWR Blend and MetaPWR Assist

As you can see, these products complement each other beautifully!

• MetaPWR Blend works at the cellular level to modulate fat cell behavior and prevent excessive fat accumulation.*
• MetaPWR Assist helps stabilize blood sugar levels, reducing energy crashes and preventing the body from converting excess glucose into fat.*

Together, they provide a holistic approach to metabolic health, addressing two of the most significant factors that influence your metabolism: fat storage and blood sugar management.*

_* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.